Tables for
Volume F
Crystallography of biological macromolecules
Edited by E. Arnold, D. M. Himmel and M. G. Rossmann

International Tables for Crystallography (2012). Vol. F, ch. 8.2, pp. 205-210   | 1 | 2 |

Chapter 8.2. Laue crystallography: time-resolved studies

K. Moffata*

aDepartment of Biochemistry and Molecular Biology, The Center for Advanced Radiation Sources, and The Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, USA
Correspondence e-mail:


Amorós, J. L., Buerger, M. J. & Canut de Amorós, M. (1975). The Laue Method. New York: Academic Press.
Bourgeois, D., Ursby, T., Wulff, M., Pradervand, C., Legrand, A., Schildkamp, W., Labouré, S., Srajer, V., Teng, T. Y., Roth, M. & Moffat, K. (1996). Feasibility and realization of single-pulse Laue diffraction on macromolecular crystals at ESRF. J. Synchrotron Rad. 3, 65–74.
Campbell, J. W. (1995). LAUEGEN, an X-windows-based program for the processing of Laue X-ray diffraction data. J. Appl. Cryst. 28, 228–236.
Cassetta, A., Deacon, A., Emmerich, C., Habash, J., Helliwell, J. R., McSweeney, S., Snell, E., Thompson, A. W. & Weisgerber, S. (1993). The emergence of the synchrotron Laue method for rapid data collection from protein crystals. Proc. R. Soc. London Ser. A, 442, 177–192.
Chen, Y. (1994). PhD thesis, Cornell University, USA.
Clifton, I. J., Duke, E. M. H., Wakatsuki, S. & Ren, Z. (1997). Methods Enzymol. 277, 448–467.
Clifton, I. J., Elder, M. & Hajdu, J. (1991). Experimental strategies in Laue crystallography. J. Appl. Cryst. 24, 267–277.
Cruickshank, D. W. J., Helliwell, J. R. & Johnson, L. N. (1992). Time-Resolved Macromolecular Crystallography. Oxford: Oxford Science Publications.
Cruickshank, D. W. J., Helliwell, J. R. & Moffat, K. (1987). Multiplicity distribution of reflections in Laue diffraction. Acta Cryst. A43, 656–674.
Cruickshank, D. W. J., Helliwell, J. R. & Moffat, K. (1991). Angular distribution of reflections in Laue diffraction. Acta Cryst. A47, 352–373.
Garman, E. F. & Schneider, T. R. (1997). Macromolecular cryocrystallography. J. Appl. Cryst. 30, 211–237.
Hajdu, J. & Johnson, L. N. (1993). Biochemistry, 29, 1669–1675.
Helliwell, J. R. (1984). Synchrotron X-radiation protein crystallography: instrumentation, methods and applications. Rep. Prog. Phys. 47, 1403–1497.
Helliwell, J. R. (1985). Protein crystallography with synchrotron radiation. J. Mol. Struct. 130, 63–91.
Helliwell, J. R., Habash, J., Cruickshank, D. W. J., Harding, M. M., Greenhough, T. J., Campbell, J. W., Clifton, I. J., Elder, M., Machin, P. A., Papiz, M. Z. & Zurek, S. (1989). The recording and analysis of synchrotron X-radiation Laue diffraction photographs. J. Appl. Cryst. 22, 483–497.
Helliwell, J. R. & Rentzepis, P. M. (1997). Time Resolved Diffraction. Oxford University Press.
Kalman, Z. H. (1979). On the derivation of integrated reflected energy formulae. Acta Cryst. A35, 634–641.
Moffat, K. (1989). Time-resolved macromolecular crystallography. Annu. Rev. Biophys. Biophys. Chem. 18, 309–332.
Moffat, K. (1995). Proc. Soc. Photo-Opt. Instrum. Eng. 2521, 182–187.
Moffat, K. (1997). Laue diffraction. Methods Enzymol. 277B, 433–447.
Moffat, K. (1998). Ultrafast time-resolved crystallography. Nature Struct. Biol. 5, 641–643.
Moffat, K., Bilderback, D., Schildkamp, W., Szebenyi, D. & Teng, T.-Y. (1989). In Synchrotron Radiation in Structural Biology, edited by R. M. Sweet and A. J. Woodhead, pp. 325–330. New York and London: Plenum Press.
Moffat, K., Szebenyi, D. & Bilderback, D. (1984). X-ray Laue diffraction from protein crystals. Science, 223, 1423–1425.
Perman, B. (1999). PhD thesis, University of Chicago, USA.
Perman, B., Šrajer, V., Ren, Z., Teng, T.-Y., Pradervand, C., Ursby, T., Bourgeois, D., Schotte, F., Wulff, M., Kort, R., Hellingwerf, K. & Moffat, K. (1998). Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle. Science, 279, 1946–1950.
Ren, Z., Bourgeois, D., Helliwell, J. R., Moffat, K., Šrajer, V. & Stoddard, B. L. (1999). Laue crystallography: coming of age. J. Synchrotron Rad. 6, 891–917.
Ren, Z. & Moffat, K. (1994). Laue crystallography for studying rapid reactions. J. Synchrotron Rad. 1, 78–82.
Ren, Z. & Moffat, K. (1995a). Quantitative analysis of synchrotron Laue diffraction patterns in macromolecular crystallography. J. Appl. Cryst. 28, 461–481.
Ren, Z. & Moffat, K. (1995b). Deconvolution of energy overlaps in Laue diffraction. J. Appl. Cryst. 28, 482–493.
Ren, Z., Ng, K., Borgstahl, G. E. O., Getzoff, E. D. & Moffat, K. (1996). Quantitative analysis of time-resolved Laue diffraction patterns. J. Appl. Cryst. 29, 246–260.
Schlichting, I., Almo, S. C., Rapp, G., Wilson, K., Petratos, K., Lentfer, A., Wittinghofer, A., Kabsch, W., Pai, E. F., Petsko, G. A. & Goody, R. S. (1990). Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis. Nature (London), 345, 309–315.
Schlichting, I. & Goody, R. S. (1997). Methods Enzymol. 277B, 467–490.
Šrajer, V., Teng, T.-Y., Ursby, T., Pradervand, C., Ren, Z., Adachi, S., Schildkamp, W., Bourgeois, D., Wulff, M. & Moffat, K. (1996). Photolysis of the carbon monoxide complex of myoglobin: nanosecond time-resolved crystallography. Science, 274, 1726–1729.
Stoddard, B. L., Cohen, B. E., Brubaker, M., Mesecar, A. D. & Koshland, D. E. Jr (1998). Millisecond Laue structures of an enzyme-product complex using photocaged substrate analogues. Nature Struct. Biol. 5, 891–897.
Wakatsuki, S. (1993). In Data Collection and Processing, edited by L. Sawyer, N. W. Isaacs & S. Bailey, pp. 71–79. DL/Sci/R34. Warrington: Daresbury Laboratory.
Wood, I. G., Thompson, P. & Mathewman, J. C. (1983). A crystal structure refinement from Laue photographs taken with synchrotron radiation. Acta Cryst. B39, 543–547.
Yang, X., Ren, Z. & Moffat, K. (1998). Structure refinement against synchrotron Laue data: strategies for data collection and reduction. Acta Cryst. D54, 367–377.